2 inflammatory response in neurological disorders and brain injury
Báo cáo hóa học: " Plasticity in neurological disorders and challenges for noninvasive brain stimulation (NBS)" pptx
Ngày tải lên :
19/06/2014, 08:20
... NeuroEngineering and Rehabilitation 2009, 6:4 application of a non-specific NBS intervention in stroke is unlikely to be successful Other acute disorders include traumatic brain and spinal cord injury and inflammatory ... therapy, brain damage can occur anywhere within the brain including subcortical structures, white matter tracts, cerebral cortex and underlying white matter, cerebellum, brainstem etc, and be of ... abnormalities manifest in cortical structures, including changes in cortical inhibition and shifts in the cortical representation of hand muscles which can occur in both early and late stages of...
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Báo cáo y học: "Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis" ppsx
Ngày tải lên :
09/08/2014, 14:21
... strongest influences of the genetic marker observed in our cohort were a significant association with non-erosive joint disease and a decreased inflammatory response in carriers of the deletion In addition, ... of those clinical associations in two additional study cohorts indicates that the influence of the deletion on the clinical disease course is a relevant and potentially clinically meaningful observation ... CCR5 d32 [33] Expression levels of CCR5, in turn, have been reported to be increased in active and decreased in less active disease, and a good clinical response to anti-TNFα treatment might be...
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Báo cáo y học: "Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dosedependent, phase IV clinical trial." pdf
Ngày tải lên :
10/08/2014, 09:22
... events included seizure and stroke Acute kidney injury was assessed applying RIFLE [15] criteria (>100% creatinine increase, using preoperative and highest creatinine concentration during the ... end-point outcome (IR) Mixed ANOVA was used to compare means between groups in clinical signs (bleeding) and laboratory parameters (D-dimer, creatine kinase and troponin I) at baseline, h and 24 ... IL-6 and D-dimer, chest-tube bleeding, norepinephrine dose, temperature, troponin I (TnI), creatine kinase (CK), MB isoenzyme creatine kinase (CK-MB) and blood pressure were assessed using Spearman’s...
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Báo cáo y học: "Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice" ppsx
Ngày tải lên :
13/08/2014, 21:21
... and MAPKs •The innate immune response to bacterial flagellin promotes systemic inflammation and triggers apoptotic signalling in the intestine • Flagellin/TLR5 signaling may be instrumental in ... flagellin (as evaluated in the lung, Figure 1d), pointing to the lack of inducibility of TLR5 in the presence of its ligand Flagellin diffusely activates NFB and MAP kinase signaling in tissues ... overexpressing the antiapoptotic protein Bcl-2 in their intestinal epithelium [32,33] Here we sought to determine the ability of flagellin to initiate apoptotic signaling in mouse organs, by determining...
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Báo cáo sinh học: "Effects of major histocompatibility complex on antibody response in F 1 and F 2 crosses of chicken lines" ppt
Ngày tải lên :
14/08/2014, 19:22
... the F and the C line may be interpreted as interaction between MHC and other immune response genes Moreover, linkage disequilibrium created in the selected lines between MHC genes and linked ... Geno2! and Geno being the rj estimated effects of MHC genotypes of haplotypes i and j, and r and j, respectively, and p being the number of pairwise combinations Methods II and III were applied in ... within genotypes were normal and ranged between those of the 114-124 and 119-121, as shown in figure the Ab response to SRBC estimated in the H, C and L lines (Pinard et al, 1993) are shown in...
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Advanced Topics in Neurological Disorders Edited by Ken-Shiung Chen pdf
Ngày tải lên :
23/03/2014, 17:20
... measuring and recording cranial posture in a dynamic manner Measurement of the declination and inclination was performed by inclinometers Inclinometers are widely used instruments for measuring ... retina are presented with cones in green and rods in pink This outlines that the repartition of cones and rods varies on the retina surface according to the distance to the Advanced Topics in Neurological ... inaccessible to humans, in environmental protection and monitoring, in ship hull and infrastructure inspection, in infrastructure inspection of nuclear power plants, in military applications,...
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báo cáo hóa học:" Optical imaging of the peri-tumoral inflammatory response in breast cancer" docx
Ngày tải lên :
18/06/2014, 15:20
... cytokines, chemokines, metalloserine and metallocysteine proteases, reactive oxygen species, and histamine, all of which augment tumor remodeling and angiogenesis [4-6] Chronic B-cell activation and ... p-value less than 0.05 Injection of free DiD resulted in no increase in fluorescent intensity within the tumor at any time point post-infusion Figure labeling (a) Optical imaging of DiD-labeled cells ... recruitment and poor prognosis [32,33] Jin et al demonstrated a role for integrin alpha beta in the homing of monocytes to tumors Specifically, the group noted that blocking this integrin in a mouse...
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báo cáo hóa học: " Upper limb impairments associated with spasticity in neurological disorders" pptx
Ngày tải lên :
19/06/2014, 10:20
... NeuroEngineering and Rehabilitation 2007, 4:45 Introduction The movement impairments following neurological illness such as stroke and spinal cord injury are caused by disturbances in descending ... Competing interests The author(s) declare that they have no competing interests Authors' contributions CT participated in performing the experiment, analyzing and interpreting the data, and writing ... movement and speed range not examined in earlier studies Differences in the experimental apparatus used for studying single- and multi-joint movements introduce inconsistencies between our work and...
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Báo cáo y học: "Decreased GABAB receptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation" pot
Ngày tải lên :
10/08/2014, 05:21
... receptors in the cerebellum and brain stem The binding data were confirmed by competition binding assay with [3H] GABA against different concentrations of GABA GABA affinity in the cerebellum and brain ... of epinephrine supplementation, alone and even in combination with glucose and oxygen, by studying the changes in GABAB receptor, expression of GABAB receptor and GAD in the brain stem and cerebellum ... with an increase in the log (EC50 )-1 indicating a shift in high affinity towards low affinity Ki(L) also showed an increase in hypoxic neonatal rats with an increase in log (EC50)-2 denoting a...
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Báo cáo y học: "Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome: a cross sectional study" pptx
Ngày tải lên :
11/08/2014, 03:20
... significantly influences the micro-inflammatory response Invariably, Waist and BMI are used inter-changeably in the definition of the Rogowski et al Journal of Inflammation 2010, 7:35 http://www.journal-inflammation.com/content/7/1/35 ... and drafted the paper SB and IS conceived the study, participated in its design and coordination and helped to draft and review the manuscript TF, TC and OKB helped in the data organization and ... between the presence of micro-inflammation and changes in each individual component of the MetS, even in individuals without defined MetS Theoretically, our findings can be used to support the...
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Báo cáo y học: "Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome: a cross sectional study" doc
Ngày tải lên :
11/08/2014, 06:22
... significantly influences the micro-inflammatory response Invariably, Waist and BMI are used inter-changeably in the definition of the Rogowski et al Journal of Inflammation 2010, 7:35 http://www.journal-inflammation.com/content/7/1/35 ... and drafted the paper SB and IS conceived the study, participated in its design and coordination and helped to draft and review the manuscript TF, TC and OKB helped in the data organization and ... between the presence of micro-inflammation and changes in each individual component of the MetS, even in individuals without defined MetS Theoretically, our findings can be used to support the...
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Báo cáo y học: " Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD" doc
Ngày tải lên :
12/08/2014, 13:22
... 80% After drying for hour, the cytospins were wrapped in aluminum foil and stored at -80°C pending immunocytochemical staining Immunocytochemical staining Frozen cytospins of BAL and sputum were ... azide 0.1% (w/v) and hydrogen peroxide 0.18% (w/v) in PBS for 30 minutes Non-specific binding was blocked in PBS, 1% bovine serum albumin (BSA) and 5% normal human serum (NHS) for 45 minutes for the ... membrane-bound CD163 staining on BAL and sputum cells A BAL cytospin is shown in the left photograph and a sputum cytospin in the right photograph Scale bar = 20 μm figures and The percentage and number of...
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Báo cáo y học: "Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor α but not estrogen receptor " pot
Ngày tải lên :
12/08/2014, 14:21
... 5% formic acid and processed and evaluated as described [33] Hematoxylin and eosin-stained sections (7 μM) were used to study joint inflammation The severity of inflammation in joints was scored ... streptavidin-PE was added and incubated for 10 minutes The Bioplex-protein assay reader from Luminex was used The amount (pg) of cytokine/chemokine per mg protein (pg/mg) was calculated Cytokine and ... reduced inflammatory cytokine production in the synovium It remains to be established whether the data in the preclinical models can be translated to the clinical setting Discussion Our main finding...
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Báo cáo y học: " Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells" docx
Ngày tải lên :
12/08/2014, 18:20
... compounds in cigarette smoke involve a combination of direct and indirect effects on cells, but principally center around an increase in airway inflammation as a result of cigarette smoking The ... involves activation of ERK1/2 and NFκB Materials and methods Reagents RPMI 1640, penicillin, streptomycin, fungizone, and trypsin/EDTA were obtained from Cellgro (Herndon, VA, USA) Fetal bovine ... MAPKs in the HBE cell line BEAS-2B [8] and that metals in the air pollutant, residual oil fly ash, can induce expression of IL-6 and IL-8 in NHBEs [17] However, the role of metals in CSC-induced...
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Báo cáo y học: "Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trial" doc
Ngày tải lên :
13/08/2014, 08:21
... which is the use of aprotinin [5] Like aprotinin, tranexamic acid (TA) inhibits fibrinolysis (that is, plasmin activity and D-dimer formation), but its effect on IR remains unclear Additionally, ... previous days and the first 24 hours following intervention After informed written consent was obtained, patients were randomly assigned by independent pharmacists using a list of pseudorandomized ... of heparin followed by an initial dose of mg/kg and further doses when necessary to achieve and maintain an activated clotting time of 480 seconds To reverse the effect of heparin, protamine was...
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Báo cáo y học: "Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype" ppsx
Ngày tải lên :
14/08/2014, 20:22
... biological responses to toxicants (for example, histopathology and clinical chemistry), referred to as 'phenotypic anchoring', allowed investigators to gain new insight into the processes involved in ... low dose In fact, in most instances this exposure dose did not elicit any injury at any of the time points However, the galactosamine and thioacetamide samples grouped together Interestingly, these ... establishing whether blood transcript data could provide insights into the presence and severity of injury within a target organ upon toxicant exposure In previously published work using these same in- life...
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Tài liệu An International Perspective on Topics in Sports Medicine and Sports Injury Edited by Kenneth R. Zaslav docx
Ngày tải lên :
20/02/2014, 08:20
... Glutamine and Glutamate Reference Intervals as a Clinical Tool to Detect Training Intolerance During Training and Overtraining 41 Rodrigo Hohl, Lỏzaro Alessandro Soares Nunes, Rafael Alkmin Reis, ... Glutamine and Glutamate Reference Intervals as a Clinical Tool to Detect Training Intolerance During Training and Overtraining Rodrigo Hohl1, Lỏzaro Alessandro Soares Nunes1, Rafael Alkmin Reis1, ... interval training, strength training, speed training, skill and tactical training, in various proportions according to the period Rugbymen and rugbywomen underwent an heavy training mostly based...
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Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt
Ngày tải lên :
19/06/2014, 08:20
... pilot randomized clinical trial in patients with acquired brain injury José-Antonio Gil-Gómez1*, Roberto Lloréns1, Mariano Alcañiz1,3 and Carolina Colomer2 Abstract Background: Acquired brain injury ... patient to play in standing or in sitting position to improve balance control in both conditions In standing position the patients are required to maintain their soles on the WBB In sitting position, ... 283.11 478.00 ± 324.77 Time since injury (days) NS (p = 0.204) The table shows the information of the patients Age and time since injury are defined in terms of mean and standard deviation Etiology...
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AN INTERNATIONAL PERSPECTIVE ON TOPICS IN SPORTS MEDICINE AND SPORTS INJURY doc
Ngày tải lên :
27/06/2014, 11:20
... Glutamine and Glutamate Reference Intervals as a Clinical Tool to Detect Training Intolerance During Training and Overtraining 41 Rodrigo Hohl, Lỏzaro Alessandro Soares Nunes, Rafael Alkmin Reis, ... Glutamine and Glutamate Reference Intervals as a Clinical Tool to Detect Training Intolerance During Training and Overtraining Rodrigo Hohl1, Lỏzaro Alessandro Soares Nunes1, Rafael Alkmin Reis1, ... interval training, strength training, speed training, skill and tactical training, in various proportions according to the period Rugbymen and rugbywomen underwent an heavy training mostly based...
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Báo cáo y học: " Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial" ppsx
Ngày tải lên :
13/08/2014, 11:22
... Thoracic injury 0.13 Abdominal injury 0.34 Extremities injury 0.20 Diffuse injury without brain swelling 12 0.046 Diffuse bilateral brain swelling 12 Diffuse unilateral brain swelling with midline ... reactivity (n)a One reacting Both reactingb 12 14 Diffuse injury without brain swelling Diffuse bilateral brain swelling Diffuse injury unilateral brain swelling with midline shift Any mass lesion ... 0.03) In nonresponding patients, we chose to place a lumbar drainage in five, in three we opted for surgical treatment, and in three other patients we combined both treatments, drainage and surgery...
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